Increase in somatostatin immunoreactivity in the suprachiasmatic nucleus of aged Wistar rats.
نویسندگان
چکیده
Decreased immunoreactivity has been reported for several neuropeptides in the aged suprachiasmatic nucleus (SCN). We compared somatostatin (SS) and substance P (SP) immunoreactivity (ir) in aged (20-26 months) and young (6 months) Wistar rats. The old rat SCN revealed a significant increase in SSir (2.6-fold) and SPir. The results show that not all SCN-neuropeptidergic systems decline with age, and suggest a specific age-related role for SS in the SCN.
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ورودعنوان ژورنال:
- Brain research
دوره 958 2 شماره
صفحات -
تاریخ انتشار 2002